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. 2021 Nov 10;6:383. doi: 10.1038/s41392-021-00779-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Exosomal ncRNA-based therapeutics in human diseases. Endogenous (pre-loading cargoes into donor cells followed by exosomal cargo release) or exogenous (directly loading cargoes into exosomes after their production or isolation) loading of ncRNAs or their inhibitors into exosomes exhibits significant therapeutic potential. ASO antisense oligonucleotide. This figure was created with the aid of Servier Medical Art (https://smart.servier.com/)