TABLE 4.
Univariate and multivariate analyses of overall survival in ADC.
| Variable | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| 5-year OS (%) | 95% CI | p | Hazard ratio | 95% CI | p | ||
| Gender | 0.002 | ||||||
| Male | 62.0 | 57.3–66.7 | Ref | ||||
| Female | 72.0 | 67.9–76.1 | 0.7 | 0.6–0.9 | 0.001 | ||
| Age | 0.335 | ||||||
| <65 | 68.0 | 64.5–71.5 | |||||
| ≥65 | 64.4 | 57.3–71.5 | |||||
| Smoking | 0.183 | ||||||
| No | 69.4 | 65.5–73.3 | |||||
| Yes | 64.1 | 59.2–69.0 | |||||
| Family History | 0.341 | ||||||
| No | 66.8 | 63.5–70.1 | |||||
| Yes | 70.8 | 62.2–79.4 | |||||
| TNM stage | <0.001 | ||||||
| I | 78.1 | 74.6–81.6 | Ref | ||||
| II | 62.0 | 53.4–70.6 | 1.8 | 1.3–2.5 | 0.001 | ||
| III | 45.4 | 38.9–51.9 | 3.1 | 2.4–4.0 | <0.001 | ||
| CEA group | <0.001 | ||||||
| Normal preoperative CEA (A) | 71.6 | 68.3–74.9 | Ref | ||||
| Normalized Postoperative CEA (B) | 60.8 | 51.4–70.2 | 1.1 | 0.8–1.5 | 0.676 | ||
| Elevated Postoperative CEA (C)) | 31.8 | 20.6–43.0 | 1.9 | 1.4–2.7 | <0.001 | ||