TABLE 1.
Association of clinicopathological data and expression of TP53 in ESCC patients.
| Patient characteristics |
TP53 expression
|
χ2 | P-value | |
| High (n = 59) | Low (n = 6) | |||
| Age | 0.437 | 0.508 | ||
| <65 | 28 | 2 | ||
| ≥65 | 31 | 4 | ||
| Gender | 0.271 | 0.603 | ||
| Male | 45 | 4 | ||
| Female | 14 | 2 | ||
| Tumor size | 0.538 | 0.764 | ||
| <3 cm | 15 | 2 | ||
| 3–5 cm | 40 | 4 | ||
| >5 cm | 4 | 0 | ||
| Tumor location | 1.06 | 0.589 | ||
| Upper | 9 | 1 | ||
| Middle | 40 | 3 | ||
| lower | 10 | 2 | ||
| TNM stage | 12.2 | 0.007* | ||
| I | 7 | 4 | ||
| II | 31 | 2 | ||
| III | 19 | 0 | ||
| IV | 2 | 0 | ||
| Lymph node metastasis | 4.697 | 0.030* | ||
| Yes | 27 | 0 | ||
| No | 32 | 6 | ||
| Differention | 1.036 | 0.596 | ||
| Well | 20 | 1 | ||
| Moderate | 27 | 4 | ||
| Poor | 12 | 1 | ||
Using a Fisher’s exact test. The p-value was set at 0.05 and * indicates p < 0.05.