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. 2021 Oct 27;12:717047. doi: 10.3389/fmicb.2021.717047

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Copyright © 2021 Wang, Zhang, Shang, Gao, Du, Li, Gao, Qi, Guo, Qu and Dong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Spatial Location of synthesized antigen peptides and proteins on Hexon Trimers in this study. The ASR was the hexon model of ancestral sequences, also called N1M1 in main text. ADV3 was the hexon model of human adenovirus type 3 strain GB. The ADV5 was the hexon model of human adenovirus type 5, which was adopted from 1P30 in RCSB (PDB) database. The ADV7 was the hexon model of human adenovirus type 7 strain Gomen. The antigen polypeptides were colored with red or green, while the antigen protein segments were colored with blue.