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. 2021 Oct 27;8:759026. doi: 10.3389/fsurg.2021.759026

Table 1.

Clinical and pathological characteristics of the patients related to the size of the tumor.

Tumor size ≤ 2 cm (1,471) Tumor size >2 and ≤4 cm (1,624) Tumor size >4 cm (1,438) P
Age (years) 46.7 ± 9.4 48.9 ± 9.8 49.2 ± 9.7 0.000
Menopausal state 0.000
 Yes 497 696 612
 No 974 928 826
BMI (kg/m2) 21.7 ± 3.3 22.3 ± 3.5 22.1 ± 3.6 0.000
FIGO 0.000
  ≤ IB1 1366 0 0
 IB2 0 1287 0
 IB3 0 0 958
 IIA1 105 337 0
 IIA2 0 0 487
Parametrial involvement 0.000
 Positive 18 (1.2%) 101 (6.2%) 322 (22.4%)
 Negative 1453 (98.8%) 1523 (93.8%) 1116 (77.6%)
Depth of stromal invasive 0.000
 ≥1/2 194 (13.2%) 1061 (65.3%) 1292 (89.8%)
  <1/2 1277 (86.8%) 563 (34.7%) 146 (10.2%)
Infiltration into vagina 0.000
 Positive 105 (7.1%) 337 (20.8%) 480 (33.4%)
 Negative 1366 (92.9%) 1287 (79.2%) 958 (66.6%)
Surgical vaginal margin 0.000
 Positive 41 (2.8%) 136 (8.4%) 180 (12.5%)
 Negative 1430 (97.2%) 1488 (91.6%) 1258 (87.5%)
Status of pelvic lymph nodes 0.000
 Positive 78 (5.3%) 288 (17.7%) 593 (41.2%)
 Negative 1393 (94.7%) 1336 (82.3%) 845 (58.8%)
Histological subtype 0.000
 Squamous cell cancer 1115 (75.8%) 1349 (83.1%) 1213 (84.4%)
 Adenocarcinoma 268 (18.2%) 180 (11.1%) 157 (10.9%)
 Adenosequamous cancer 76 (5.2%) 75 (4.6%) 56 (3.9%)
 Other subtype 12 (0.8%) 20 (1.2%) 12 (0.8%)
Infiltration into uterine body 0.000
 Positive 39 (2.7%) 219 (13.5%) 474 (33%)
 Negative 1432 (97.3%) 1405 (86.5%) 964 (67%)
Lymph vascular space invasion 0.000
 Positive 299 (20.3%) 887 (64.6%) 917 (63.8%)
 Negative 1172 (79.7%) 737 (45.4%) 521 (36.2%)
Recurrence 0.000
 Positive 29 (2.0%) 101 (6.2%) 199 (13.8%)
 Negative 1433 (97.4%) 1504 (92.6%) 1194 (83.0%)
 Unknown 9 (0.6%) 19 (1.2%) 45 (3.2%)
Survival state 0.000
 Death 28 (1.9%) 105 (6.5%) 233 (16.2%)
 Live 1443 (98.1%) 1519 (93.5%) 1205 (83.8%)
 Unknown 0 (0%) 0 (0%) 0 (0%)