Table 4.

The univariable and multivariable Cox regression model analyses of the parametrial invasion in the training cohort.

	Univariable analysis		Multivariable analysis
	OR (95%CI)	P	OR (95%CI)	P
Age (year)
<40	Reference		NR
≥40 <60	1.061 (0.775–1.453)	0.710
≥60	1.399 (0.939–2.086)	0.099
Histological subtype
Squamous cell cancer	Reference		Reference
Adenocarcinoma	0.654 (0.442–0.969)	0.034	0.859 (0.534–1.380)	0.859
Adenosequamous cancer	0.716 (0.382–1.342)	0.298	0.947 (0.468–1.967)	0.947
Other subtype	1.094 (0.427–2.798)	0.852	1.005 (0.328–3.078)	0.993
Surgical vaginal margin
Negative	Reference		Reference
Positive	4.718 (3.520–6.322)	<0.001	1.288 (0.875–1.896)	0.199
Depth of stromal invasive
<1/2	Reference		Reference
≥1/2	19.533 (11.374–33.547)	<0.001	3.128(1.675–5.842)	<0.001
Tumor size
≤ 2cm	Reference		Reference
>2 and ≤ 4 cm	5.277 (2.908–9.574)	<0.001	1.426 (0.722–2.818)	0.307
>4cm	21.712 (12.322–38.259)	<0.001	2.907 (1.489–5.678)	0.002
Infiltration into vagina
Negative	Reference		Reference
Positive	6.425 (5.039–8.192)	<0.001	2.926 (2.146–3.990)	<0.001
Infiltration into uterine body
Negative	Reference		Reference
Positive	4.832 (3.772–6.188)	<0.001	1.736 (1.289–2.338)	<0.001
Lymph vascular space invasion
Negative	Reference		Reference
Positive	6.107 (4.533–8.227)	<0.001	1.847 (1.305–2.612)	0.001
Status of pelvic lymph nodes
Negative	Reference		Reference
Positive	14.579 (11.163–19.041)	<0.001	5.504 (4.156–7.556)	0.001