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. 2021 Apr 19;114(3):1012–1027. doi: 10.1093/ajcn/nqab063

TABLE 4.

Pearson correlation coefficients (r) and FDR-corrected P values for changes in serum protein concentrations, DASH score, and asthma control parameter (ACQ) score, and changes in the dietary biomarkers and CRP from baseline to 3 mo1

Folate Carotene Vitamin B-12 Vitamin D CRP
Serum protein r FDR P value r FDR P value r FDR P value r FDR P value r FDR P value
Th2-related
 IL-4 0.24 0.67 −0.27 0.36 −0.20 0.74 −0.04 0.96 0.07 0.89
 IL-5 0.29 0.672 −0.22 0.40 −0.06 0.90 0.09 0.96 0.00 0.99
 IL-13 0.05 0.84 −0.26 0.37 −0.17 0.74 −0.03 0.96 0.22 0.70
 Eotaxin 0.22 0.68 −0.09 0.73 −0.09 0.90 0.00 1.00 −0.17 0.70
Th1-related
 IL-12P40 0.11 0.74 −0.09 0.73 −0.17 0.74 −0.10 0.96 0.33 0.292
 IL-12P70 0.21 0.68 −0.30 0.36 −0.15 0.83 0.06 0.96 0.00 0.99
 IFN-γ 0.19 0.68 −0.18 0.44 −0.06 0.90 0.10 0.96 −0.08 0.88
 IP-10 0.26 0.67 −0.31 0.362 −0.05 0.90 −0.12 0.96 0.19 0.70
 MIG/CXCL9 0.09 0.82 0.05 0.89 −0.20 0.74 0.25 0.82 −0.25 0.61
Th17-related
 IL-17F −0.16 0.68 0.11 0.69 −0.03 0.98 0.26 0.82 0.17 0.70
 IL-17 0.03 0.91 −0.20 0.40 0.33 0.492 0.24 0.82 0.05 0.92
Regulatory
 IL-10 0.19 0.68 −0.21 0.40 −0.18 0.74 −0.04 0.96 0.11 0.79
Inflammatory
 IL-1α 0.07 0.84 −0.25 0.38 −0.18 0.74 −0.03 0.96 0.27 0.49
 IL-1β 0.24 0.67 −0.17 0.46 0.00 1.00 −0.04 0.96 −0.03 0.92
 IL-2 0.16 0.68 −0.23 0.40 −0.13 0.87 0.01 0.96 0.15 0.70
 IL-6 0.16 0.68 −0.28 0.36 0.01 0.99 0.14 0.96 0.09 0.87
 IL-8 −0.18 0.68 0.02 0.94 −0.06 0.90 −0.01 0.96 0.04 0.92
 IL-15 0.15 0.68 −0.29 0.36 −0.12 0.87 0.10 0.96 0.14 0.71
 IFN-β 0.02 0.94 −0.21 0.40 0.08 0.90 0.22 0.82 0.31 0.292
 TGF-α 0.12 0.71 −0.28 0.36 −0.08 0.90 0.04 0.96 0.15 0.70
 TGF-β 0.06 0.84 −0.13 0.61 0.08 0.90 0.11 0.96 0.03 0.92
 TNF-α 0.11 0.71 −0.22 0.40 −0.31 0.492 −0.05 0.96 0.11 0.79
 MIP-1α 0.06 0.84 −0.03 0.93 0.11 0.89 0.23 0.82 0.16 0.70
 MIP-1β 0.13 0.68 −0.17 0.46 0.05 0.92 0.13 0.96 −0.16 0.70
 MCP-1 0.28 0.67 −0.27 0.36 −0.17 0.74 −0.10 0.96 0.07 0.89
 MCP-3 0.13 0.68 −0.29 0.36 −0.21 0.74 0.01 0.96 0.18 0.70
 RANTES 0.13 0.68 −0.08 0.75 0.02 0.98 −0.07 0.96 0.03 0.92
 Resistin 0.01 0.94 0.11 0.68 −0.36 0.492 −0.26 0.82 0.50 <0.052
 CD40L 0.03 0.94 0.21 0.40 −0.14 0.84 −0.06 0.96 0.03 0.92
Adhesion
 ICAM-1 0.08 0.83 0.00 0.99 0.05 0.90 0.03 0.96 0.06 0.89
 VCAM-1 0.14 0.68 0.09 0.73 −0.29 0.492 −0.18 0.96 0.07 0.89
Inflammation-associated growth factors
 IL-7 0.26 0.67 −0.27 0.36 −0.14 0.84 0.03 0.96 −0.10 0.79
 VEGF 0.18 0.68 −0.18 0.44 0.02 0.98 0.15 0.96 −0.15 0.70
 G-CSF 0.11 0.71 −0.22 0.40 0.02 0.98 0.22 0.82 0.23 0.65
 GM-CSF 0.14 0.68 −0.22 0.40 −0.25 0.63 0.01 0.96 0.10 0.79
 NGF 0.14 0.68 −0.27 0.36 −0.02 0.98 0.07 0.96 0.14 0.71
Other growth factors
 LIF 0.24 0.67 −0.21 0.40 −0.11 0.87 −0.03 0.96 0.04 0.92
 SCF 0.17 0.68 −0.18 0.44 −0.09 0.90 −0.01 0.96 0.10 0.79
 FGFβ 0.15 0.68 −0.30 0.362 0.07 0.90 0.09 0.96 0.01 0.97
 HGF 0.08 0.83 −0.14 0.57 −0.25 0.63 −0.23 0.82 0.42 0.102
Other
 Leptin −0.04 0.88 0.09 0.73 −0.33 0.492 0.01 0.96 −0.06 0.89
 PAI-1 0.25 0.67 0.02 0.94 −0.06 0.90 −0.08 0.96 0.15 0.70
 FASL 0.07 0.84 −0.18 0.44 0.03 0.98 0.10 0.96 0.06 0.89
 ENA-78 0.01 0.94 0.00 0.99 0.00 1.00 0.10 0.96 0.30 0.332
 PDGFBB 0.16 0.68 −0.11 0.68 −0.12 0.87 0.09 0.96 −0.11 0.79
 TRAIL 0.08 0.83 −0.03 0.94 −0.11 0.87 0.10 0.96 0.17 0.70
 IL-1RA −0.02 0.94 −0.06 0.84 −0.22 0.74 −0.03 0.96 0.35 0.292
 DASH score −0.21 0.68 0.03 0.94 −0.18 0.74 −0.13 0.96 0.20 0.70
 ACQ 0.06 0.84 −0.19 0.44 −0.21 0.74 −0.24 0.82 0.15 0.70
1

ACQ, Asthma Control Questionnaire; CRP, C-reactive protein; DASH, Dietary Approaches to Stop Hypertension; ENA-78, epithelial-derived neutrophil-activating peptide 78; FASL, soluble Fas ligand; FDR, false discovery rate; FGF, fibroblast growth factor; G-CSF, granulocyte colony stimulatory factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; HGF, hepatocyte growth factor; ICAM-1, soluble intercellular adhesion molecule 1; IP-10, interferon γ–induced protein 10; LIF, leukemia inhibitory factor; MCP, macrophage colony-stimulating factor; MIG/CXCL9, monokine induced by γ interferon; MIP, macrophage inflammatory protein; NGF, nerve growth factor; PAI-1, plasminogen activator inhibitor 1; PDGFBB, platelet-derived growth factor-BB; RANTES, regulated on activation, normal T-cell expressed and secreted; SCF, stem cell factor; TGF, transforming growth factor; Th, T-helper; VCAM-1, soluble vascular cell adhesion molecule 1; VEGF, vascular endothelial growth factor.

2

Indicates correlation coefficients with original P values of <0.05.