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. 2021 Oct 27;11:758653. doi: 10.3389/fonc.2021.758653

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Copyright © 2021 Zhou, Liu, Zhou, Chen, Xie, Yao and Cui

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Properties and biological functions of MALAT1. (A) Affects gene transcription. (B) Affects the alternative splicing of pre-mRNAs. (C) Regulates protein activity. (D) Mediates epigenetic changes. (E) Promotes nuclear and cytoplasmic translocation of cellular proteins. (F) Acts as an endogenous miRNA sponge.