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. 2021 Oct 27;11:754788. doi: 10.3389/fonc.2021.754788

Figure 1.

Figure 1

Overview of the study design and microbiota profiling. (A) Schematic overview of the study design. TCMA, the cancer microbiome atlas; TCGA, the cancer genome atlas; ESCA, esophageal carcinoma; ESCC, esophageal squamous cell carcinoma; EAD, esophageal adenocarcinoma. (B–F) The composition of microbiota with an average abundance > 1% in tumor and paired normal tissues at the phylum, class, order, family, and genus levels, respectively. The relative microbial abundance in tumors compared with normal samples, ^0.1 < P < 0.01, *P < 0.05, **P < 0.01 in paired-samples t-test.