Table 2.
Multivariate Cox regression analysis of the independent significance of eight microbes as prognostic factors.
| Microbes | HR | HR (0.95 lower) | HR (0.95 upper) | P-value | |
|---|---|---|---|---|---|
| Phylum | Proteobacteria | 5.61E-02 | 1.27E-03 | 2.48E+00 | 0.136 |
| Class | Clostridia | Inf | Inf | Inf | <2E-16 |
| Fusobacteriia | 3.94E-86 | 3.47E-87 | 4.48E-85 | <2E-16 | |
| Negativicutes | 7.34E-03 | 7.57E-07 | 7.11E+01 | 0.294 | |
| Order | Clostridiales | 0.00E+00 | 0.00E+00 | 0.00E+00 | <2E-16 |
| Fusobacteriales | 1.11E+86 | 9.81E+84 | 1.27E+87 | <2E-16 | |
| Family | Lactobacillaceae | 0.00E+00 | 0.00E+00 | Inf | 0.988 |
| Genus | Lactobacillus | 1.60E+298 | 0.00E+00 | Inf | 0.994 |
HR, hazard ratio. The results were analyzed by multivariate Cox regression model based on “survival” package in R.
There were four microbes with P < 0.05 in the multivariate Cox regression analysis, as showed in bold values.