Table 3.
Diagnostic performance of 5 guidelines.
| Method | Cut-off | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | AUC |
|---|---|---|---|---|---|---|---|
| ACR-TIRADS | |||||||
| 5 | 73.9 (69.4-78.1) |
70.5 (67.0-73.9) |
60.4 (57.2- 63.4) |
81.7 (79.09-84.1) |
71.8 (69.0- 74.5) |
0.763 (0.736-0.791) |
|
| P value | 0.012a | <0.001a | 0.007a | 0.439a | 0.029a | <0.001a;0.004b;0.305c | |
| Kwak-TIRADS | 4C | 89.9 (86.5- 92.6) |
62.0 (58.3- 65.7) |
58.9 (56.5- 61.3) |
91.0 (88.3- 93.1) |
72.5 (69.8-75.2) |
0.789 (0.763-0.815) |
| P value | <0.001a | <0.001a | 0.001a | <0.001a | 0.071a | <0.001a | |
| EU-TIRADS | 5 | 88.2 (84.7- 91.1) |
55.4 (51.6- 59.2) |
54.6 (52.3-56.8) |
88.5 (85.5- 91.0) |
67.8 (64.9- 70.6) |
0.734 (0.705-0.763) |
| P value | <0.001a | <0.001a | <0.001a | <0.001a | <0.001a | <0.001a;<0.001b;<0.001c;<0.001d | |
| KTA/KSThR-TIRADS | 5 | 81.6 (77.6- 85.3) |
66.7 (63.0-70.3) |
59.8 (57.0- 62.6) |
85.7 (82.9- 88.1) |
72.4 (69.6- 75.0) |
0.773 (0.746-0.800) |
| P value | <0.001a | <0.001a | 0.037a | 0.708a | 0.043a | <0.001a;0.014b | |
| C-TIRADS | 4C | 75.7 (70.9- 80.3) |
82.3 (79.2- 85.1) |
69.2 (65.3-72.8) |
79.8 (77.45-81.9) |
76.0 (73.4-78.5) |
0.816 (0.791-0.841) |
95% confidence intervals are in parentheses; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the receiving operator characteristics curve; P value, aCompared with C-TIRADS; bCompared with Kwak-TIRADS; cCompared with KTA/KSThR-TIRADS; dCompared with ACR-TIRADS.