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. 2021 Nov 9;11(11):e052449. doi: 10.1136/bmjopen-2021-052449

Table 1.

Clinical studies on Bifidobacterium infantis

Reference No of participants* Main results
28 80 Safe consumption and good tolerance of B. infantis; stools significantly fewer and better formed.
29 66 Significant changes to faecal microbiome composition; colonisation with B. infantis; higher abundance of faecal short chain fatty acids; lower stool pH.
30 40 Lower faecal calprotectin levels; lower enteric inflammation.

*Participants in total, meaning the group of children B. infantis fed and the group placebo fed (for all: treatment from day 7 on, dose 1.8–2.8×1010 colony forming units), all participants were breastfed infants.