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. 2021 Oct 27;9:761847. doi: 10.3389/fcell.2021.761847

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Copyright © 2021 Hu, Komal, Singh and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hair cell protein expression and distortion product otoacoustic emission (DPOAE) study. Representative DPOAE waveforms of Nefl^CreER/+;iDTR^+/– mice treated with either diphtheria toxin (DT) or vehicle are shown in (A). In the quantitative study, DPOAE measurements at 4 weeks old did not show a significant difference between the DT and vehicle treatments at 16 (A1) or 24 kHz (A2) in the P14 or P21 groups (two-way ANOVA: p > 0.05, n = 6 mice/group). In the surface preparation of Nefl^CreER/+;iDTR^+/– mice treated with either DT or vehicle on P14, the numbers of myosin VIIa-expressing cells are statistically insignificant (B,B1; ANOVA: p > 0.05, n = 5 mice/group). n.s. statistically insignificant. Scale, 25 μm in (B).