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Interference footprinting assays performed with oligo tel1 variants containing substitutions of residues N4 and N5. Formic acid (FA) and KMnO4 interference assays were carried out as described in the legend to Fig. 3. For each reagent, one control lane (c) and one experimental lane (i) are shown in panel I, and the corresponding histograms are presented in panel II. (A) Formic acid (10%) assays of oligo tel2. (B) Formic acid (10%) assays and 0.15 mM KMnO4 assays of oligo tel3.
