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. 2020 May 23;79(5):599–614. doi: 10.1093/nutrit/nuaa013

Table 2.

Summary of studies

Area studied Total no. of studies Study types No. of positive-quality studies No. of neutral-quality studies No. of negative-quality studies Fermented products studied Comparators No. of studies with favorable outcome No. of studies with no significant effect No. of studies with unfavorable outcome
Gastrointestinal health and disease 26
  • RCT=16

  • RCOT=8

  • CS=1

  • NRCT=1

19 6 1 Yogurt, fermented milk, fermented milk drinks, pasteurized yogurt, probiotic yogurt, kefir Dahi, ultra-heated yogurt, nonfermented dairy product, milk, pasteurized yogurt, acidified milk, yogurt, lactose water, ice cream, ice milk, frozen yogurt, hydrolyzed lactose milk, lactase tablet, fermented/cultured milk 20 6 0
Cardiovascular health and disease 28
  • RCT=7

  • RCOT=5

  • CC=1

  • CS=4

  • CH=11

8 19 1 Yogurt, probiotic yogurt, fermented milk, probiotic fermented milk with added biopeptides Chemically fermented dairy, pasteurized yogurt, 2% butterfat milk, probiotic cheese, probiotic yogurt, nonfermented dairy product, 2% milk, nonfat milk, low-fat yogurt, no milk, no yogurt 16 11 1
Weight 22
  • RCT=5

  • CS=8

  • CH=9

7 15 0 Yogurt, kefir Milk, chemically fermented milk, isoenergetic sucrose beverage, low-dairy calcium diet 19 3 0
Cancer 17
  • RCT=1

  • CC=5

  • CH=11

1 16 0 Yogurt, fermented milk No yogurt 9 5 3
Diabetes 9
  • RCT=1

  • RCOT=2

  • CS=1

  • CH= 5

2 5 1 Yogurt, probiotic in fermented milk Sweetened yogurt, skim milk, orange juice, no supplementation, nonfermented milk 7 1 0
Bone health 7
  • RCT=1

  • CS=3

  • CH=3

1 6 0 Yogurt, laban No yogurt 5 2 0

Abbreviations: CC, case-control (study); CH, cohort (study); CS, cross-sectional (study); NRCT, nonrandomized controlled trial; RCOT, randomized crossover trial; RCT, randomized controlled trial.