Fig. 1.

Visuomotor assessment tasks. Visual representation of the saccade (a), tapping (b) and trajectory prediction (c) tasks performed by patients P1 and P2, and respective age-matched controls. Pro-tasks involved the execution of reflexive saccades (and tapping) towards a newly appeared target while anti-tasks required a saccade execution (and tapping) to the opposite side of the new target. In memory tasks, subjects waited for target omission to perform a saccade (and tapping). Trajectory prediction tasks involved the execution of a saccade and tapping towards the basket in which a moving ball would be expected to fall. The number and age distribution of control participants per task can be found in Table 1.