Fig. 6.
Social behaviour is largely preserved in p110δE1020Kmice. a) Example of automatically tracked body positions during test phase (novel mouse on the left). b) Total time individual mice spent in each chamber of the apparatus during test phase (mixed effects model; data presented as median with interquartile range). c) Before and after plot of the total time each individual mouse spent on the novel mouse chamber during baseline (BL) and test (T) (2-way repeated-measures ANOVA). d) Body position heatmap depicting position frequency per 2.5 mm bins (novel mouse on the left). e) Median and quartiles with the ratio between the time each individual mouse spent near the social cup over the time it spent near the empty cup (2-tailed t-test). f) Representative plot with the duration, in seconds, of each transition into the empty (light bars) or novel mouse (dark bars) cup area. g) Median and quartiles with the percentage of transitions each individual mouse made to the novel mouse or empty cup (2-way repeated-measures ANOVA); h) Median and quartiles of the ratio between the time individual mice spent exploring the novel mouse cup over the time spent in the whole novel mouse chamber (2-tailed t-test). ∗p ≤ 0.05, ∗∗p ≤ 0.01, ∗∗∗p ≤ 0.001. n = 15 mice per genotype.