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. 2021 Apr 14;22(5):bbab091. doi: 10.1093/bib/bbab091

Figure 3 .

Figure 3

Functional analysis of novel seeds and their canonical seeds. (A) Some miRNA loci show significant differences between target mRNAs of novel seeds and their canonical seeds based on hypergeometric tests. (B) An example of functional analysis of isomiRs in miR-21-5p. b1: Distribution of candidate targets between total novel seeds and canonical seeds; b2: a Venn diagram of targets among detailed seeds; b3: number of CGC genes among different seeds; b4: distribution of cancer hallmarks among different seeds. (C) An example of functional analysis of isomiRs in miR-143-3p locus. c1: Distribution of targets among novel seeds and canonical seeds; c2: distribution of cancer hallmarks among different seeds.