Table 2. Adjusted Associations Between Maternal Psychosocial Factors During Pregnancy and Neonatal Line Widths Measured at the Cuspal, Midcrown, and EDJ Adjacent Portionsa.
| Exposure | β (SE) [95% CI] | P value | FDR-adjusted P value | Model overall R2 |
|---|---|---|---|---|
| Cuspal portion (mean [SD], 11.83 [4.97] μm) | ||||
| Severe lifetime depression history | 1.59 (2.03) [−2.47 to 5.64] | .44 | .44 | 0.11 |
| Any lifetime psychiatric problem | 1.59 (1.84) [−2.09 to 5.27] | .39 | .43 | 0.11 |
| Maternal depression or anxiety, 32 gestational weeks | 1.90 (1.96) [−2.02 to 5.82] | .34 | .40 | 0.11 |
| High social support, 8 wk post partum | −3.48 (1.72) [−6.92 to −0.04] | .048 | .11 | 0.16 |
| Middle portion (mean [SD], 9.87 [3.8] μm) | ||||
| Severe lifetime depression history | 1.93 (1.47) [−1.00 to 4.86] | .19 | .29 | 0.22 |
| Any lifetime psychiatric problem | 2.01 (1.33) [−0.64 to 4.66] | .13 | .23 | 0.23 |
| Maternal depression or anxiety, 32 gestational weeks | 1.64 (1.43) [−1.21 to 4.49] | .25 | .34 | 0.22 |
| High social support, 8 wk post partum | −2.36 (1.23) [−4.83 to 0.10] | .06 | .12 | 0.32 |
| EDJ portion (mean [SD], 7.34 [2.46] μm) | ||||
| Severe lifetime depression history | 3.35 (0.94) [1.48 to 5.23] | <.001 | .01 | 0.24 |
| Any lifetime psychiatric problem | 2.66 (0.87) [0.92 to 4.41] | .003 | .02 | 0.20 |
| Maternal depression or anxiety, 32 gestational weeks | 2.29 (0.96) [0.38 to 4.20] | .02 | .06 | 0.16 |
| High social support, 8 wk post partum | −2.04 (0.83) [−3.70 to −0.38] | .02 | .06 | 0.18 |
Abbreviations: EDJ, enamel-dentine junction; FDR, false discovery rate.
Mean (SD) of each neonatal line portion are noted in the section headers to provide a reference for interpreting the magnitude of effect estimates. In these adjusted models, the following covariates were included: gestational age (continuous or weeks), maternal obesity before pregnancy (with 0 indicating a body mass index <30 and 1 indicating a BMI of 30 or greater [calculated as weight in kilograms divided by height in meters squared]), and maternal iron supplement during pregnancy (with 0 indicating did not take iron supplement and 1 indicating took iron supplement). These maternal or birth-related factors were selected as covariates because they were associated with the neonatal line width in bivariate analyses (eMethods in the Supplement).