Table 1.
Baseline Characteristics
| Demographic and Clinical | Hysterectomy (n=727) | Myomectomy (n=568) | P |
|---|---|---|---|
| Age (y) | 45.2±4.9 | 40.2±6.0 | <.01 |
| Race White | 50.3 (366) | 41.0 (233) | <.01 |
| African American | 37.8 (275) | 41.0 (233) | |
| Other | 11.8 (86) | 18.0 (102) | |
| BMI (kg/m2) | 31.2±8.0 | 28.7±7.8 | <.01 |
| Age at first leiomyoma diagnosis (y) | 38.7±7.8 | 35.4±7.0 | <.01 |
| Age of first leiomyoma symptoms (y) | 38.2±8.2 | 34.9±7.4 | <.01 |
| Duration of symptoms (y) | 7.1±7.1 | 5.4±5.3 | <.01 |
| Specific symptoms | 94.5 (687) | 93.7 (532) | .48 |
| Bleeding between periods | 52.8 (384) | 45.6 (259) | <.01 |
| Nocturia | 59.0 (429) | 50.5 (287) | <.01 |
| Abdominal or pelvic pressure | 73.3 (533) | 67.3 (382) | .02 |
| Pelvic pain requiring medication | 47.5 (345) | 37.7 (214) | <.01 |
| Nonmenstrual pain | 30.4 (221) | 23.4 (133) | <.01 |
| Family history of leiomyomas—yes | 50.8 (369) | 54.8 (311) | <.01 |
| Any prior treatment | 19.9 (145) | 15.1 (86) | .03 |
| Endometrial ablation | 4.3 (31) | 1.1 (6) | <.01 |
| Uterine artery embolization | 3.0 (22) | 0.7 (4) | <.01 |
| Regular, predictable menses | 53.9 (392) | 69.7 (396) | <.01 |
| History of anemia | 55.0 (400) | 48.0 (273) | <.01 |
| Ever pregnant | 77.7 (565) | 56.2 (319) | <.01 |
| 2 or more pregnancies | 63.3 (460) | 35.9 (204) | <.01 |
| Other medical condition | 50.6 (368) | 41.7 (237) | <.01 |
| Endometriosis | 9.8 (71) | 6.2 (35) | .02 |
| Adenomyosis | 3.7 (27) | 0.7 (4) | <.01 |
| Ever use: marijuana | 26.4 (192) | 33.1 (188) | .03 |
| HRQOL | |||
| UFS-QOL | |||
| Subscales (lower means more severe) Concern | 38.3±29.9 | 44.8±31.4 | <.01 |
| Activities | 45.8±28.7 | 52.2±28.7 | <.01 |
| Energy/mood | 45.2±26.8 | 51.4±26.8 | <.01 |
| Control | 48.5±27.3 | 51.7±26.5 | .03 |
| Self-consciousness | 41.2±31.0 | 48.5±32.2 | <.01 |
| Sexual function | 45.4±33.5 | 52.1±34.2 | <.01 |
| Total (sum of subscales) | 44.0±25.4 | 50.2±25.3 | <.01 |
| UFS-QOL symptom severity (higher means more severe) | 60.7±23.6 | 51.7±24.6 | <.01 |
| EQ-5D without problem | |||
| Mobility | 72.6 (528) | 82.4 (468) | <.01 |
| Self-care | 91.9 (668) | 93.70 (532) | .13 |
| Usual activities | 60.1 (437) | 65.9 (374) | .11 |
| Pain/discomfort | 16.8 (122) | 26.6 (151) | <.01 |
| Anxiety/depression | 39.1 (284) | 40.3 (229) | .75 |
| VAS (lower means lower QOL) | 69.3±20.4 | 73.4±18.9 | <.01 |
BMI, body mass index; HRQOL, health-related quality of life; UFS-QOL, Uterine Fibroid Symptom Quality of Life; EQ-5D, EuroQoL 5-Dimension Health Questionnaire; VAS, visual analog scale; QOL, quality of life.
Data are mean±SD or % (n) unless otherwise specified.
Table shows only those demographic and clinical characteristics that were different at P<.05.