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. 2021 Nov 7;11(4):20458940211055996. doi: 10.1177/20458940211055996

Fig. 4.

Fig. 4.

Berk-ss and Hbbth/3+ mice demonstrate unique lung and right ventricular metabolism across the 25 most significantly changed metabolites: Multivariate analyses of metabolomics data of lungs and right ventricle (RV) of wild type (WT – green), sickle cell disease (SCA – red) and beta-thalassemia mice (blue). Analyses included principal component analysis (PCA) in (a) and (b), and hierarchical clustering analyses of the top significant 25 metabolites by ANOVA (c and d).