Table 1.
Patient’s Characteristics before Transplantation.
| Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | 43 | 27 | 57 | 18 | 39 | 57 | 36 | 40 | 27 | 46 | 34 | 36 |
| Gender | F | F | F | M | M | M | F | M | M | F | F | M |
| Lmmunophenotype of lymphoma | B | NK/T | B | T | T | B | B | NK/T | B | B | B | T |
| International Prognostic Index | 4 | 1 | 4 | 2 | 2 | 3 | 3 | 4 | 3 | 3 | 2 | 2 |
| Previous therapy | RE-CHOP | E-CHOP | RE-CHOP | LE-CHOP | E-CHOP | RE-CHOP | RE-CHOP | L-CHOP | E-CHOP | R-CHOP | RE-CHOP | E-CHOP |
| HLH’s presentation | ||||||||||||
| Fever (T>38.5°C) | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| Hepato/splenomegaly (n) | Y | N | N | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| Hemophagocytosis | Y | Y | Y | Y | Y | Y | N | Y | Y | Y | Y | Y |
| WBC (*109/L) | 2.5 | 2.4 | 1 | 0.5 | 2.96 | 5.7 | 1.65 | 5.32 | 2.8 | 7.31 | 1.71 | 6.03 |
| HGB (g/L) | 128 | 85 | 59 | 102 | 116 | 132 | 79 | 97 | 121 | 76 | 63 | 127 |
| PLT (*109/L) | 27 | 171 | 61 | 61 | 10 | 55 | 71 | 25 | 171 | 239 | 4 | 328 |
| Ferritin (ng/ml) | 1218 | 601 | 4097.8 | 1500 | 7816 | 1046 | 26169 | 1500 | 5726 | 2685 | 2694 | 2000 |
| sCD25 (pg/mL) | 44000 | 7202.2 | 29678 | 44000 | 44000 | 41419 | 39008 | 44000 | 6983 | 31820 | 44000 | 2317 |
| NK-cell activity (%) | 9.05 | 14.06 | 3.68 | 14.28 | 25.87 | 14.17 | 13.94 | 16.53 | 15.33 | 14.91 | 17.91 | 14.71 |
| ALT (U/L) | 207 | 111 | 15 | 95 | 124 | 146 | 35 | 48 | 94 | 10 | 20 | 59 |
| AST (U/L) | 249 | 99.2 | 12.5 | 204 | 117 | 265 | 30 | 61 | 100 | 18 | 47 | 26 |
| Fbg (g/L) | 0.89 | 0.84 | 3.88 | 2.12 | 2.31 | 4.13 | 5.53 | 1.7 | 2.6 | 4.29 | 4.81 | 4.97 |
| TG (mmol/L) | 5.68 | 3 | 1.07 | 2.03 | 5.93 | 5.2 | 6.48 | 2.71 | 2 | 2.7 | 4.92 | 2.56 |
| EBV-DNA (PBMC) copies/ml | 0 | <500 | <500 | 0 | <500 | <500 | 0 | - | <500 | 5.7*105 | 0 | 0 |
| EBV-DNA (plasma) copies/ml | 0 | <500 | 0 | 0 | 0 | <500 | 0 | 4.60*104 | 3.30*104 | 4.50*104 | 0 | 0 |