Table 1.

Longitudinal echocardiographic examination of the sham and non-treatment groups throughout the entire experimental time-intervals.

	Sham							Non-treatment
Time/week	0	0.5	1	2	3	4.5	6	0	0.5	1	2	3	4.5	6
IVSd (mm)	1.1 ± 0.13	1.12 ± 0.1	1.22 ± 0.13	1.19 ± 0.07	1.33 ± 0.2	1.19 ± 0.16	1.14 ± 0.23	1.15 ± 0.14	1.22 ± 0.12*	1.20 ± 0.08	1.19 ± 0.11**	1.54 ± 0.15**	1.68 ± 0.28	1.73 ± 0.34**
LVIDd (mm)	6.91 ± 0.47	6.86 ± 0.72	6.85 ± 0.41	6.86 ± 0.55	6.95 ± 0.51	6.91 ± 0.68	6.92 ± 0.61	6.92 ± 0.43	7.01 ± 0.38	7.03 ± 0.34	6.99 ± 0.63	7.08 ± 0.53	7.12 ± 0.53	7.12 ± 0.56
LVPWd (mm)	1.5 ± 0.25	1.43 ± 0.25	1.47 ± 0.25	1.47 ± 0.26	1.61 ± 0.36	1.54 ± 0.26	1.4 ± 0.33	1.55 ± 0.29	1.82 ± 0.28	1.67 ± 0.17	1.81 ± 0.43	1.53 ± 0.21	1.73 ± 0.31	1.89 ± 0.31*
IVSs (mm)	2 ± 0.34	1.88 ± 0.28	2.03 ± 0.28	1.99 ± 0.44	2.01 ± 0.37	2.06 ± 0.23	2.21 ± 0.43	1.97 ± 0.4	2.18 ± 0.35	2.45 ± 0.16*	2.56 ± 0.4*	2.49 ± 0.23*	2.51 ± 0.38	2.62 ± 0.43*
LVIDs (mm)	4 ± 0.53	4.19 ± 0.42	4.22 ± 0.41	4.13 ± 0.41	4.42 ± 0.48	4.54 ± 0.72	4.23 ± 0.43	3.88 ± 0.4	4.22 ± 0.4	4.14 ± 0.34	4.01 ± 0.55	3.94 ± 0.44	4.01 ± 0.39	4.03 ± 0.53
LVPWs (mm)	2.3 ± 0.24	2.27 ± 0.27	2.34 ± 0.31	2.42 ± 0.37	2.33 ± 0.45	2.23 ± 0.29	2.47 ± 0.29	2.22 ± 0.17	2.5 ± 0.38	2.58 ± 0.23	2.67 ± 0.59**	2.41 ± 0.16	2.63 ± 0.36	2.67 ± 0.46*
FS(%)	42.11 ± 5.1	38.92 ± 4.46	38.42 ± 5.21	39.79 ± 6.25	36.40 ± 7.94	34.3 ± 5.85	38.87 ± 3.82	43.93 ± 4.11	39.80 ± 5.11	41.11 ± 4.35	42.63 ± 5.23	44.35 ± 3.74	43.68 ± 7.29	43.40 ± 5.43
E wave velocity	92.9 ± 11.31	99.67 ± 5.31	90.42 ± 11.88	91.68 ± 9.34	95.03 ± 9.55	96.38 ± 14.58	97.72 ± 16.27	96.88 ± 11.01	95.33 ± 16.99	102.67 ± 7.23	94.67 ± 8.12	101.53 ± 11.2	101.76 ± 19.3	110.67 ± 23.6
E′ IVS	6.1 ± 1.71	6.13 ± 1.21	5.68 ± 1.05	5.45 ± 1.09	6.43 ± 1.88	5.34 ± 0.77	5.4 ± 1.1	5.23 ± 0.65	6.4 ± 1.83	6.92 ± 1.2	4.78 ± 1.26	6.01 ± 1.09	5.15 ± 1.16	6.23 ± 1.52
E′ FW	6.7 ± 1.98	6.73 ± 1.32	6.28 ± 1.41	6.07 ± 0.9	6.98 ± 2.07	6.31 ± 1.2	6.23 ± 1.53	6.15 ± 1.04	8.2 ± 1.26**	7.17 ± 1.66	5.98 ± 1.28	7.19 ± 2.03	5.95 ± 1.85	7.72 ± 1.93
DAP (mmHg)	51.42 ± 5.57	53.5 ± 6.26	58 ± 13.72	54.67 ± 6.02	53.58 ± 9.35	57.3 ± 14.16	56.17 ± 7.91	54.25 ± 19.99	56.5 ± 12.8	63 ± 8.54	70 ± 13.51	67.67 ± 10.14	70.3 ± 10.61	59.33 ± 12.46
MAP (mmHg)	66.19 ± 4.9	68.75 ± 3.54	72.28 ± 9.62	67.14 ± 6.12	67.92 ± 6.52	69.3 ± 10.5	72.11 ± 5.15	69.08 ± 17.6	74.25 ± 8.65	77.57 ± 6.71	84.47 ± 10.41	80.25 ± 14.7	85.6 ± 11.9**	77.75 ± 11.46
RWT	0.38 ± 0.05	0.37 ± 0.08	0.39 ± 0.06	0.39 ± 0.05	0.42 ± 0.04	0.4 ± 0.04	0.4 ± 0.03	0.39 ± 0.04	0.43 ± 0.03	0.41 ± 0.05	0.43 ± 0.06	0.43 ± 0.08	0.48 ± 0.05	0.51 ± 0.09*

Note: Values are expressed as mean  ± SD (n = 12). IVSd: interventricular septum diastolic diameter. LVIDd: left ventricular internal diastolic diameter; LVPWd: left ventricular posterior wall diastolic diameter; IVSs: interventricular septum systolic diameter; LVIDs: left ventricular internal systolic diameter; LVPWs: left ventricular posterior wall systolic diameter; FS: fraction shortening; E wave velocity: velocity of early mitral inflow ; E′ IVS: early diastolic velocity of the septum; E′ FW: early diastolic velocity of the free wall; DAP: diastolic artery pressure; MAP: mean artery pressure; RWT: relative wall thickness.

*p < 0.05 and **p < 0.01 refer to the significance of the comparison along the study period (in weeks) in the non-treatment and sham groups using two-way ANOVA, n = 12.