FIG. 3.

CR1 is necessary and sufficient for the regulation of mRNA stability by the p38 pathway. Transfections and ribonuclease protection assays were performed as described in the legend to Fig. 2, using the reporter constructs pTetBBB-Cox1.4, -Cox0.6, -Cox0.5, and -Cox0.1. SB, 1 μM SB203580. (A) Representative experiments. Only the β-globin reporter and GAPDH loading control bands are shown. (B) Graphical representation of the experiments shown in panel A. Each transfection was performed at least twice, with qualitatively identical results.