Table 2.
Participant characteristics at randomisation in the randomised controlled trials linked to the National Pupil Database
| NEP | NETSGA | LCPUFAP | LCPUFAT | IRONT | PALMT | NUCLEOT | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MF | SF | MF | SF | MF | SF | MF | SF | MF | SF | MF | SF | MF | SF | |||||||
| Linked/randomised* | 108/113 | 114/116 | 135/152 | 134/147 | 82/96 | 89/100 | 137/155 | 143/154 | 149/162 | 150/165 | 98/103 | 92/100 | 90/100 | 86/100 | ||||||
| Birth weight (g) | 1392 (775-2160) | 1363 (630-2020) | 2538 (1400-3160) | 2597 (1770-3160) | 1351 (640-1850) | 1344 (740-1780) | 3654 (2960-4900) | 3532 (2680-4930) | 3483 (2495-5046) | 3468 (2466-4706) | 3588 (2460-4730) | 3472 (2520-5400) | 3453 (2210-4720) | 3482 (2170-5360) | ||||||
| Gestational age (weeks) | 30.8 (26-36) | 30.8 (25-36) | 39.1 (37-42) | 39.4 (37-42) | 30.5 (25-36) | 30.1 (25-36) | 40.1 (37-42) | 40.0 (37-42) | 39.7 (36-43) | 39.9 (35-43) | 40.1 (37-42) | 39.9 (37-42) | 39.5 (37-42) | 39.2 (37-42) | ||||||
| Mother’s age | 28.0 (16-41) | 28.5 (17-44) | 26.9 (15-42) | 26.6 (16-42) | 26.2 (16-39) | 26.6 (17-39) | 27.8 (17-44) | 27.0 (18-41) | 27.8 (17-40) | 27.6 (15-39) | 27 (15-40) | 28 (17-42) | 27 (16-38) | 27 (16-40) | ||||||
| Sex: | ||||||||||||||||||||
| Male | 51 (47) | 56 (49) | 68 (50) | 63 (47) | 38 (46) | 47 (53) | 73 (53) | 77 (54) | 76 (51) | 76 (51) | 62 (63) | 46 (50) | 55 (61) | 47 (55) | ||||||
| Female | 57 (53) | 58 (51) | 67 (50) | 71 (53) | 44 (53) | 42 (47) | 64 (47) | 66 (46) | 73 (49) | 74 (49) | 36 (37) | 46 (50) | 36 (39) | 39 (45) | ||||||
| Mother smoked during pregnancy: | ||||||||||||||||||||
| No | 64 (62) | 74 (68) | 69 (55) | 62 (51) | 46 (56) | 54 (61) | 102 (76) | 104 (75) | 108 (73) | 104 (71) | 62 (63) | 69 (75) | 65 (73) | 51 (60) | ||||||
| Yes | 38 (38) | 35 (32) | 57 (45) | 59 (49) | 36 (44) | 35 (39) | 32 (24) | 35 (25) | 40 (27) | 43 (29) | 36 (37) | 23 (25) | 24 (27) | 34 (40) | ||||||
| Missing (No) | 4 | 5 | 9 | 13 | 0 | 0 | 3 | 4 | 1 | 3 | 0 | 0 | 1 | 1 | ||||||
| Mother has degree: | ||||||||||||||||||||
| No | 102 (94) | 96 (88) | 130 (96) | 127 (95) | 49 (92) | 44 (92) | 124 (92) | 135 (96) | 130 (88) | 136 (92) | † | † | 83 (92) | 77 (92) | ||||||
| Yes | 6 (6) | 13 (12) | 5 (4) | 6 (5) | 4 (8) | 4 (8) | 11 (8) | 6 (4) | 18 (12) | 12 (8) | † | † | 7 (8) | 7 (8) | ||||||
| Missing (No) | 0 | 5 | 0 | 1 | 29 | 41 | 2 | 2 | 1 | 2 | 71 | 73 | 0 | 2 | ||||||
Data are mean (minimum-maximum) or number (%), unless indicated otherwise.
MF=modified formula, SF=standard formula; DHA=docosahexaenoic acid; AA=arachidonic acid.
Trials: NEP=nutrient enriched post-discharge formula for babies born preterm; NETSGA=nutrient enriched term formula for babies born at term and small for gestational age; LCPUFAP=preterm formula supplemented with long chain polyunsaturated fatty acids (0.17% DHA + 0.31% AA) for babies born preterm; LCPUFAT=term formula supplemented with long chain polyunsaturated fatty acids (0.32% DHA + 0.30% AA) for babies born at term; IRONT=term follow-on formula with high iron content (12 mg/L iron) for babies born at term; PALMT=term formula with sn-2 palmitate for babies born at term; NUCLEOT=term formula with added nucleotides for babies born at term.
Number/total randomised study population (irrespective of survival).
Suppressed because of low numbers.