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Lipid metabolism regulates the occurrence and development of tumors by regulating lncRNAs. Lipid metabolites and enzymes involved in lipid metabolism can in turn regulate the expression of lncRNAs to participate in tumor progression. For example, cholesterol regulates lncRNA HULC to promote liver cancer progression, palmitic acid regulates lncRNA UCA1 to promote gastric cancer metastasis, and PLD regulates lncRNA ANRIL to exert an anti-large cell lung cancer effect.
