Table 1.

Summary of lipid metabolism-associated lncRNAs in cancer

LncRNA	Associated type of effect	Target	Influence to target	Cancer type	Reference
LncRNA SNHG16	Cholesterol synthesizes	SREBP2	Up	Pancreatic cancer	45
Lnc030	Cholesterol synthesizes	SQLE	Up	Breast cancer	47
LncRNA CASC19	Cholesterol uptake	LDLR	Up	Non-small cell lung cancer	48
LncRNA TINCR	De novo synthesis of fatty acids	ACLY	Up	Nasopharyngeal carcinoma	77
LncRNA FLJ22763	De novo synthesis of fatty acids	ACLY	Down	Gastric cancer	78
LncRNA DNAJC3-AS1	De novo synthesis of fatty acids	ACC/FASN	Up	Colorectal cancer	87
LncRNA CTD-2245E15. 3	De novo synthesis of fatty acids	ACC1	Up	Non-small cell lung cancer	85
LncRNA HAGLR	De novo synthesis of fatty acids	FASN	Up	Non-small cell lung cancer	94
LncRNA HOTAIR	De novo synthesis of fatty acids	FASN	Up	Nasopharyngeal carcinoma	96
LncRNA PVT1	De novo synthesis of fatty acids	FASN	Up	Osteosarcoma	98
LncRNA SNHG16	De novo synthesis of fatty acids	SCD	Up	Colorectal cancer	104
LncRNA uc.372	De novo synthesis of fatty acids	ACC/FASN/SCD1	Up	Liver cancer	105
LncRNA UPAT	De novo synthesis of fatty acids	SCD1	Up	Colon cancer	107
LncRNA uc.372	Exogenous uptake of fatty acids	CD36	Up	Liver cancer	105
LncRNA LNMICC	Exogenous uptake of fatty acids	FABP5	Up	Cervical cancer	120
LncRNA SNHG7	Oxidation of fatty acids	ACSL1	Up	Thyroid cancer	130
LncRNA HULC	Oxidation of fatty acids	ACSL1	Up	Hepatocellular carcinoma	132
LncRNA NEAT1	Oxidation of fatty acids	ACSL4	Up	Prostate cancer	131
LncRNA MACC1-AS1	Oxidation of fatty acids	CPT1	Up	Gastric cancer	121
LncRNA HCP5	Oxidation of fatty acids	CPT1	Up	Gastric cancer	142
LncRNA AGAP2-AS1	Oxidation of fatty acids	CPT1	Up	Breast cancer	122
LncRNA NEAT1	Oxidation of fatty acids	CPT1	Up	Breast cancer	144
LncRNA SPRY4-IT1	Synthesis of triglyceride	Lipin-2	Down	Melanoma	150
LncRNA HR1	Synthesis of triglyceride	SPEBP-1c	Down	Liver cancer	152
LncRNA NEAT1	Degradation of triglyceride	ATGL	Up	Hepatocellular carcinoma	158
LncRNA Khps1	Phospholipid metabolism	SphK1	Up	Osteosarcoma	169
LncRNA HULC	Phospholipid metabolism	SphK1	Up	Hepatocellular carcinoma	170
LINC00460	Phospholipid metabolism	SphK1	Up	Colorectal cancer	171
LINC00460	Phospholipid metabolism	SphK2	Up	Papillary thyroid carcinoma	172
LINC00520	Phospholipid metabolism	SphK2	Up	Papillary thyroid carcinoma	173
LINC00511	Phospholipid metabolism	PLD1	Up	Cervical cancer	178
LncRNA SLNCR1	Phospholipid metabolism	PLA2	Up	Non-small cell lung cancer	181
LncRNA HULC	Cholesterol	FOXM1	Up	Hepatocellular carcinoma	185
LncRNA UCA1	Palmitic acid	ERK/MMP-9	Up	Gastric cancer	190-192
LncRNA ANRIL	Phospholipid	/	/	Large cell lung cancer	193