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. 2021 Oct 11;17(15):4176–4191. doi: 10.7150/ijbs.67379

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Increased accumulation of Pd1+ CD8 T cells in tumors from SPC;sgCul3 mice compared with that in SPC mice. (A) t-SNE plots showing the identified cell clusters. (B) Dot plot showing the expression levels of marker genes for each cell population. (C) Cell cluster frequency for each mouse. (D) Comparison of cell lineages in each group. (E) Sankey diagram showing the Pd1 positive or negative fraction in each cluster from SPC and SPC;sgCul3 mice. (F) The frequency of Pd1+ T cells in SPC and SPC;sgCul3 mice (n=4).