Table 1.
The sgRNAs corresponding to top candidate genes
| Genes | UID of sgRNAs enriched in top 200 enrichment list |
|---|---|
| Trp53 | MGLibA_56035, MGLibA_56033, MGLibA_56034 |
| Cul3 | MGLibA_12475, MGLibA_12477, MGLibA_12476 |
| Fbxw7 | MGLibA_18106, MGLibA_18108, MGLibA_18107 |
| Inppl1 | MGLibA_26092, MGLibA_26094, MGLibA_26093 |
| Bgn | MGLibA_06851, MGLibA_06850, MGLibA_06849 |
| Dhcr7 | MGLibA_14046, MGLibA_14045 |
| Unc80 | MGLibA_57346, MGLibA_57345 |
| Apc | MGLibA_04599, MGLibA_04600 |
| Spta1 | MGLibA_51191, MGLibA_51192 |
| Trp53bp1 | MGLibA_56011, MGLibA_56009 |
| Rad23b | MGLibA_44346, MGLibA_44345 |
| Mlh1 | MGLibA_31447, MGLibA_31449 |
| Nrxn3 | MGLibA_34816, MGLibA_34817 |
| Slc6a13 | MGLibA_49644, MGLibA_49643 |
| Zbtb44 | MGLibA_60094, MGLibA_60095 |
The CRISPR knockout library (#1000000052, Addgene) contains 3 sgRNAs for each gene and genes that were disrupted by at least two different sgRNAs were listed.