Table 1.

Impact of perioperative drug and anesthetic management on cardiovascular control and hypoxic pulmonary vasoconstriction

	HR	MAP	SVR	PVR	CO	HPV	Raw
Intravenous Anesthetics
Ketamine	+	+	+	+/0	+	0	-
Etomidate	0	0	0	0	0	0	0
Propofol	0/-	--	--	0	-	0	0
Midazolam	0	0/-	0/-	0	0/-	0	0
Analgesics
Opiates	0	0	0	0	0	0	0 (+)
Dexmedetomidine	-	-	-	0	-	0	0
Nonsteroidal anti-inflammatory drugs	0	0	0	0	0	(-/0/+)	0
Volatil anesthetics
Isoflurane	0/-	--	--	--	--	--	-
Sevoflurane	0/-	-	-	-	-	-	-
Desflurane	0/-	-	-	-	-	-	-
Inotropes, vasopressors, bronchodilators
Dobutamine, Dopamine	+	+/0/-	0/-	0/-	+	-	0
Phenyléphrine	0/-	+	+	+	0/-	0	0
Milrinone							0 (-)
Salbutamol	+	+/0/-	+	0/-	+	-	-
Anti-hypertensive drugs	0/-	--	--	-	0/+	-
CCB	0/-	--	--	-	0/+	-	0
NTG, NPS	0/+	--	--	-	+	-	0
ACEI, ATA	0	-	-	0/-	+	0/-	0((+)
Beta-blockers	-	-	0/+	0/+	-	0	0/+

0, no change; +, increased; -, decreased; --, more decreased; CO, cardiac output; HPV, hypoxic pulmonary vasoconstriction; HR, heart rate; MAP, mean arterial pressure; PVR, pulmonary vascular resistance; Raw, airway resistance; SVR, systemic vascular resistance. ACEI, angiotensin-converting enzyme inhibitor; ATA, angiotensin II antagonist; CCB, calcium-channel blocker; NPS, nitroprussiate; NTG, nitroglycerine