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. 2021 Nov 10;21:423. doi: 10.1186/s12876-021-02009-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Pathological findings of right cervical lymph node biopsy. A Pathological findings of right cervical lymph node biopsy with hematoxylin and eosin staining indicate tumor cells in the specimen (×40) as well as B tumor cells with a signet ring cell feature (×400). C Upper endoscopy shows no abnormal findings in the pyloric region of the stomach. D Lymph node biopsy with Alcian blue-periodic acid-Schiff staining shows mucin-abundant tumor cells (×400). E Immunohistochemical staining shows positive cytokeratin (CK)-7, positive CK-20, negative thyroid transcription factor-1 (TTF-1), positive hepatocyte nuclear factor-4α (HNF-4α), positive caudal-type homeobox-2 (CDX-2), and negative napsin A (×400)