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. 2021 Nov 10;20:77. doi: 10.1186/s12941-021-00481-4

Table 4.

Baseline characteristics and clinical manifestations of uropathogenic Escherichia coli infection according to phylogenetic group

Phylogenetic group B2
(n = 276)
Phylogenetic group D
(n = 62)
p value
Age, years 69.43 ± 14.59 69.16 ± 14.13 0.893
Male sex 57 (20.7%) 4 (6.5%) 0.009
Category of UTI
 Acute pyelonephritis 269 (97.5%) 61 (98.4%) 0.999*
 Acute prostatitis 8 (2.9%) 2 (3.2%) 0.999*
 Renal abscess 20 (7.2%) 8 (12.9%) 0.144
 Prostatic abscess 4 (1.4%) 0 (0.0%) 0.999*
Category of infection
 Community-acquired 192 (69.6%) 52 (83.9%) 0.023
 Healthcare-associated 71 (25.7%) 7 (11.3%) 0.015
 Nosocomial 13 (4.7%) 3 (4.8%) 0.999*
Underlying diseases
 Solid tumor 39 (14.1%) 9 (14.5%) 0.937
 Hematologic malignancy 0 0
 Chronic liver disease 43 (15.6%) 7 (11.3%) 0.390
 Liver cirrhosis 14 (5.1%) 0 (0.0%) 0.082*
 Cardiovascular disease 75 (27.2%) 16 (25.8%) 0.826
 Hypertension 143 (51.8%) 39 (62.9%) 0.113
 Neurologic disease 98 (35.5%) 19 (30.6%) 0.467
 Chronic renal disease 14 (5.1%) 4 (6.5%) 0.753*
 Diabetes mellitus 101 (36.6%) 32 (51.6%) 0.029
 Chronic lung disease 28 (10.1%) 7 (11.3%) 0.789
 Solid organ transplantation 2 (0.7%) 0 (0.0%) 0.999*
Predisposing factors
 Pregnancy 1 (0.4%) 0 (0.0%) 0.999*
 Neurogenic bladder 24 (8.7%) 5 (8.1%) 0.873
 BPH or uterine prolapse 26 (9.4%) 2 (3.2%) 0.110
 Urogenic anomaly 4 (1.4%) 0 (0.0%) 0.999*
 Nephrectomy state (one kidney) 3 (1.1%) 1 (1.6%) 0.557*
 Neutropenia 0 0
 Previous genitourinary surgery or procedure within 72 h 0 0
 Recurrent UTI 32 (11.6%) 6 (9.7%) 0.666
 Presence of urologic devices 1 (0.4%) 0 (0.0%) 0.999*
 Intermittent catheterization 2 (0.7%) 0 (0.0%) 0.999*
 Urinary catheter 23 (8.3%) 3 (4.8%) 0.439*
 Prior antibiotics within 3 months 64 (23.2%) 12 (19.4%) 0.514
Type of UTI
 Bacteremic UTI 167 (60.5%) 44 (71.0%) 0.124
 Complicated UTI 57 (20.7%) 4 (6.5%) 0.009
 Severe UTI 94 (34.1%) 21 (33.9%) 0.978

BPH benign prostate hyperplasia, UTI urinary tract infection

*Fisher’s extract test