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. 2021 Nov 10;22:547. doi: 10.1186/s12859-021-04417-9

Table 1.

Overview of metabolic models and general polyhedra used for performance tests and comparisons of efmtool [12] and mplrs [1]. For metabolic models the number of rows corresponds to the number of metabolites and the number of columns to the number of reactions with numbers in brackets referring to the number of reversible reactions. For the metabolic models the dimensions of the original uncompressed model and a comparison between the compressions of efmtool and EFMlrs are given. For the polytopes, the matrix dimensions of the original uncompressed (uncmp.) polytope P, the transformed uncompressed and via efmtool compressed model in the flux cone FC are shown. All polytopes were obtained from the lrs homepage [27]. comp., compression; Deg., degree of degeneracy

Model uncmp. P uncmp. FC efmtool comp. EFMIrs comp. EFMs Deg.
Columns Rows Columns Rows Columns Rows Columns Rows
EColiCentral [28] 71 (15) 53 44 (11) 26 44 (11) 21 429,276 High
EColiCore2 [29] 82 (22) 54 58 (18) 30 58 (18) 30 34,896,477 High
iPS189 [30] 277 (21) 271 67 (13) 42 63 (13) 35 3,252,686 High
JCVI-syn3A [31] 316 (8) 286 100 (7) 50 100 (7) 48 ? High
cp6 [27] 16 (15) 368 384 (15) 368 384 (15) 368 32 High
bv7 [27] 57 (56) 69 106 (56) 69 49 (0) 12 5,040 High
mit71 [27] 61 (60) 71 132 (60) 71 132 (60) 71 3,149,579 Moderate
fq48-19 [27] 19 (18) 48 67 (18) 48 48 (0) 29 119,184 Moderate
mit [27] 9 (8) 729 738 (8) 729 729 (0) 720 4,862 Moderate
perm10 [27] 11 (10) 1023 1033 (10) 1023 1033 (10) 1023 3628800 Simple