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. 2021 Nov 10;17(2):214–227. doi: 10.1016/j.jtho.2021.11.001

Table 3.

Summary of COVID-19 Vaccine Effectiveness in Fully Vaccinated Patients With Cancer

Summary of COVID-19 Vaccine Effectiveness in Fully Vaccinated Patients With Cancer
Study Country/Countries Cancer Types # of Patients or Control Vaccine # of Patients or Control % Seroconversion Median Titer Level (AU/mL or U/mL)
Gounant et al.61 France Thoracic 269 Mostly BNT162b2 269 94 4725
Control 13 BNT162b2 13 10,594
Goshen-Lago et al.49 Israel Various 218 BNT162b2 218 86
Lung cancer 43 BNT162b2 43 86
Massarweh et al.50 Israel Solid cancers 102 BNT162b2 102 90 1931
Lung cancer 26 BNT162b2 26 92 1334
Control 78 BNT162b2 78 100 7160
Thakkar et al.51 U.S. Various 200 BNT162b2 115 95 5173
Thoracic/head and neck 25 mRNA-1273 62 94 11,963
Ad26.COV2.S 20 85 1121
Control 26 >15,000
Addeo et al.52 Switzerland, U.S. Various 131 BNT162b2 30 93 1232
Thoracic malignancy 18 mRNA-1273 93 95 2500
Barriere et al.5 France Solid cancers 42 BNT162b2 42 95 245
Control BNT162b2 100 2517
Monin et al.53 United Kingdom Various 24 BNT162b2 24 79
Control 12 BNT162b2 12 100

Note: Two-dose mRNA vaccines are highly effective (∼90%) in patients with cancer, though patients with cancer have lower titers than health controls.

#, number; AU, arbitrary unit; COVID-19, coronavirus disease 2019; U.S., United States.