Table 2.
Patient Clinical Characteristics and Demographic Data
| Patient demographics | ||||
|---|---|---|---|---|
| ABO-C | ABO-PE | ABO-IA | p | |
| Sex | ||||
| Male | 146 (48.5) | 9 (33.3) | 3 (30) | 0.18 |
| Female | 155 (51.5) | 18 (66.7) | 7 (70) | 0.18 |
| Ethnicity | ||||
| White | 221 (73.4) | 20 (74.1) | 5 (50) | 0.26 |
| BAME | 75 (24.9) | 7 (25.9) | 4 (40) | 0.56 |
| Unrecorded/Refused | 5 (1.7) | 0 | 1 (10) | 0.11 |
| Age at Transplant (years) | 10.7 [4.7-14.1] | 0.7 [0.5-1.3] | 4.1 [3.6-5.4] | <0.001 |
| Weight at Transplantation (kg) | 26.8 [14.2-44] | 7.5 [5.6-10] | 13.4 [11-16.4] | <0.001 |
| Pre-transplant location data | 301 (100) | 27 (100) | 10 (100) | |
| Hospital ward/HDU | 176 (58.5) | 16 (59.3) | 4 (40) | 0.5 |
| ICU | 77 (25.6) | 6 (22.2) | 5 (50) | 0.2 |
| Home | 48 (15.9) | 5 (18.5) | 1 (10) | 0.82 |
| Pre-transplant mechanical support | ||||
| None | 211 (70) | 17 (63) | 4 (40) | 0.1 |
| VAD (LVAD/BiVAD) | 81 (27) | 9 (33.3) | 6 (60) | 0.06 |
| ECMO | 35 (11.6)a | 2 (7.4)b | 3 (30)c | 0.16 |
Abbreviations: ABO-C, Compatible Heart Transplant; ABO-PE, Incompatible Heart Transplantation with Plasma Exchange; ABO-IA, Incompatible Heart Transplantation with Immunoadsorption; BAME, Black, Asian and Minority Ethnicity; HDU, High Dependency Unit; ICU, Intensive CareUnit; VAD, Ventricular Assistance Device; LVAD, Left Ventricular Assistance Device; BiVAD, Biventricular Assistance Device; ECMO, Extracorporeal Membrane Oxygenation.
Continuous variables are presented as median [interquartile range] whilst categorical data are presented as count (percentage).
a
26 patients were converted to LVAD/BiVAD.
b
1 patient was converted to LVAD/BiVAD.
c
two patients were converted to LVAD/BiVAD.