Table 1.

Bivariate and multivariate regression analysis of factors associated with severe malaria among 251 febrile patients with positive Plasmodium falciparum in microscopy test

Characteristics	Total (n=251)	Malaria characteristic
		Uncomplicated (n=180), n (%)	Severe (n=71), n (%)	cOR (95% CI)	P*	aOR (95% CI)	P**
Sex
Male	125	88 (70.4)	37 (29.6)	0.9 (0.5-1.5)	0.645	NS	NS
Female	126	92 (73.0)	34 (27.0)	Reference		NS	NS
Age (years)
0-5	154	90 (58.4)	64 (41.6)	29.5 (8.2-102.1)	<0.001	27.1 (7.3-100.6)	<0.001
6-15	26	22 (84.6)	4 (15.4)	5.7 (1.0-10.5)		6.3 (0.8-35.4)	0.057
>15	71	68 (95.8)	3 (4.2)	Reference		Reference	-
Use of insecticide-treated mosquito nets
No	38	19 (50.0)	19 (50.0)	Reference	0.002	Reference	-
Yes	213	161 (75.6)	52 (24.4)	0.3 (0.1-0.7)		0.3 (0.1-0.6)	0.002
Blood group
A	81	44 (54.2)	37 (45.8)	3.3 (1.8-5.8)	<0.001	5.3 (2.7-10.5)	<0.001
B	46	32 (69.6)	14 (30.4)	1.1 (0.6-2.3)		2.8 (0.9-4.3)	0.075
AB	7	3 (42.9)	4 (57.1)	3.5 (0.8-16.2)		3.4 (0.7-21.2)	0.199
O	117	101 (86.3)	16 (13.7)	Reference		Reference	-
Rhesus
Positive	250	179 (71.6)	71 (28.4)	NA	0.529	NS	NS
Negative	1	1 (100.0)	0	NA		NS	NS

*P calculated using pearson’s Chi-square test or Fisher’s exact test, **P calculated using logistic regression analysis. aOR: Adjusted odds ratio, cOR: Crude odds ratio, CI: Confidence interval, NA: Not applicable, NS: Not significant