Table 4 –

Genetic etiology of non-compaction cardiomyopathy

Gene	Protein	Chr	Mode of inheritance	Pediatric frequency	OMIM	Reference
ACTC1	α-Cardiac actin	15q14	AD	Rare	102540	^{128, 131, 132}
ACTN2	Actinin, α 2	1q43	AD	Rare	102573	^{128, 131, 132}
LDB3	LIM-binding domain 3	10q23	AD	Rare	605906	^{128, 131, 132}
MYBPC3	Cardiac myosin-binding protein C	11p11	AD, AR	~8%	600958	^{128, 131, 132, 137}
MYH7	β-Myosin heavy chain	14q11-q12	AD	~19%	160760	^{128, 131, 132, 137}
TNNT2	Cardiac troponin T	1q32	AD	Rare	191045	^{128, 131, 132}
TPM1	α-Tropomyosin	15q22	AD	Rare	191010	^{128, 131, 132}
TTN	Titin	2q31	AD, AR	Rare	188840	^{128, 131, 132, 137}
TAZ	Tafazzin	Zq28	XR	Rare	300394	¹³³

AD, autosomal dominant; AR, autosomal recessive; XD, X-linked dominant; XL, X-linked; XR, X-linked recessive