Table 3.
Perinatal outcomes of singletons born after single vitrified embryo transfer cycles.
| 0-3 m | 3-12 m | >12 m | p value | |||
|---|---|---|---|---|---|---|
| p | p1 | p2 | ||||
| number of cycles, n | 1812 | 1252 | 538 | |||
| gestational age (d), median (IQR) | 273 (268~278) | 273 (266~277) | 271 (266~274) | <0.001 | <0.001 | <0.001 |
| preterm birth, n (%) | 119 (6.6) | 93 (7.4) | 43 (8.0) | 0.441 | 0.592 | 0.592 |
| early preterm birth, n (%) | 14 (0.8) | 12 (1.0) | 6 (1.1) | 0.719 | 0.963 | 0.963 |
| birth weight (g), median (IQR) | 3400 (3100~3700) | 3360 (3100~3650) | 3400 (3100~3700) | 0.097 | 0.240 | 0.260 |
| SGA, n (%) | 84 (4.6) | 57 (4.6) | 19 (3.5) | 0.536 | 0.984 | 0.590 |
| AGA, n (%) | 1271 (70.1) | 889 (71.0) | 350 (65.1) | 0.036 | 0.635 | 0.043 |
| LGA, n (%) | 457 (25.2) | 306 (24.4) | 169 (31.4) | 0.006 | 0.654 | 0.008 |
| delivery mode, n (%) | 0.021 | 0.040 | 0.781 | |||
| vaginal delivery | 232 (12.8) | 123 (9.8) | 72 (13.4) | |||
| cesarean section | 1580 (87.2) | 1129 (90.2) | 466 (86.6) | |||
| newborn gender, n (%) | 0.649 | 0.711 | 0.711 | |||
| male | 1017 (56.1) | 712 (56.9) | 314 (58.4) | |||
| female | 795 (43.9) | 540 (43.1) | 224 (41.6) | |||
| complication, n (%) | ||||||
| gestational hypertension | 76 (4.2) | 59 (4.7) | 12 (2.2) | 0.049 | 0.550 | 0.072 |
| gestational diabetes mellitus | 110 (6.1) | 98 (7.8) | 30 (5.6) | 0.091 | 0.166 | 0.748 |
| placenta previa | 73 (4.0) | 75 (6.0) | 29 (5.4) | 0.041 | 0.049 | 0.322 |
| birth defects | 40 (2.2) | 32 (2.6) | 15 (2.8) | 0.686 | 0.904 | 0.904 |
SGA, small for gestational age; AGA, appropriate for gestational age; LGA, large for gestational age; IQR, interquartile range.
p: group (0-3 m) vs. group (3-12 m) vs. group (>12 m), p1: group (0-3 m) vs. group (3-12 m), p2: group (0-3 m) vs. group (>12 m).
p1 and p2 were the corresponding p values adjusted by the method “False Discovery Rate (fdr)”.