TABLE 1.

Profile of fecal metabolites in rats after 6-week prednisone treatment^a

Class	Metabolite	CON	PRED	P value
SCFAs	Valeric acid	28.1333 ± 7.0798	14.2940 ± 4.1317	0.0013
	Propanoic acid	22.7566 ± 4.4820	14.2891 ± 4.9201	0.0057
	Isobutyric acid	7.4810 ± 3.5346	2.9502 ± 1.5464	0.0140
	Isovaleric acid	1.9924 ± 0.5135	1.2237 ± 0.7155	0.0175
	Caproic acid	1.1045 ± 0.5233	0.5190 ± 0.3999	0.0379
Phenylpropanoic acids	Hydrocinnamic acid	1.2233 ± 0.3337	0.5228 ± 0.1715	0.0008
	2-Phenylpropionate	1.1960 ± 0.3175	0.5227 ± 0.1724	0.0007
	Phenyllactic acid	0.0073 ± 0.0089	0.0357 ± 0.0365	0.0262
	Hydroxyphenyllactic acid	0.0051 ± 0.0013	0.0142 ± 0.0097	0.0379
Benzenoids	Phenylacetic acid	1.4107 ± 0.5759	0.8644 ± 0.4648	0.0262
	Ortho-hydroxyphenylacetic acid	0.0028 ± 0.0004	0.0021 ± 0.0004	0.0158
	Homovanillic acid	0.0063 ± 0.0013	0.0128 ± 0.0062	0.0151
	m-Aminobenzoic acid	0.0002 ± 0.0002	0.0004 ± 0.0002	0.0495
Organic acids	Acetoacetic acid	8.7525 ± 4.1035	3.8692 ± 3.0756	0.0283
	Malonic acid	0.0024 ± 0.0009	0.0147 ± 0.0103	0.0213
	Succinic acid	0.0731 ± 0.0527	1.8185 ± 1.4589	0.0262
Fatty acids	Ethylmethylacetic acid	1.8629 ± 0.7450	0.9630 ± 0.6738	0.0262
	Methylmalonic acid	0.1356 ± 0.1168	3.6283 ± 2.8569	0.0262
	2-Hydroxy-3-methylbutyric acid	0.0096 ± 0.0135	0.0874 ± 0.0881	0.0070
Amino acids	l-Phenylalanine	0.7265 ± 0.1550	0.9887 ± 0.2590	0.0448
	l-Tryptophan	0.0333 ± 0.0230	0.0630 ± 0.0188	0.0219

^aCON, control group; PRED, prednisone group.