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Mechanisms of spore killing. (A) In the killer-target systems, all spores are exposed to the killer element encoded by the yellow locus. Only those spores that inherit the target locus (orange) are destroyed by the killer. (B) In the poison-antidote systems, the drive haplotype (yellow) encodes both a poison and an antidote. All spores are exposed to the poison, but only those that inherit the drive haplotype receive the antidote and are rescued.
