Table 2.
Univariate Cox regression of risk factors
| HR | 95% CI | P | ||
| Age∗ | 1.020 | 1.014 | 1.027 | <0.001 |
| Sex | 0.965 | 0.787 | 1.183 | 0.729 |
| APACHE II∗ | 1.063 | 1.050 | 1.076 | <0.001 |
| Hypotension∗ | 2.079 | 1.707 | 2.532 | <0.001 |
| Hyperlactacidemia∗ | 1.541 | 1.268 | 1.874 | <0.001 |
| Site of infection | ||||
| Respiratory system∗ | 1.273 | 1.030 | 1.573 | 0.025 |
| Blood stream | 1.339 | 0.947 | 1.893 | 0.099 |
| Intra-abdominal | 1.005 | 0.802 | 1.259 | 0.967 |
| Urinary system | 0.770 | 0.486 | 1.221 | 0.267 |
| Soft tissue∗ | 0.350 | 0.145 | 0.846 | 0.020 |
| Source of patient | ||||
| Emergency room | Reference | |||
| Other departments∗ | 1.253 | 1.007 | 1.559 | 0.043 |
| Operating room∗ | 0.681 | 0.478 | 0.970 | 0.033 |
| Other hospitals | 1.074 | 0.766 | 1.505 | 0.680 |
| Comorbidities | ||||
| COPD∗ | 1.396 | 1.062 | 1.837 | 0.017 |
| Asthma | 1.527 | 0.682 | 3.421 | 0.304 |
| Cardiac disease | 1.264 | 0.998 | 1.602 | 0.052 |
| Hypertension | 1.183 | 0.973 | 1.438 | 0.092 |
| Diabetes | 1.184 | 0.949 | 1.477 | 0.134 |
| Liver cirrhosis∗ | 2.396 | 1.237 | 4.642 | 0.010 |
| Cancer∗ | 1.554 | 1.143 | 2.112 | 0.005 |
| Chronic renal disease∗ | 1.459 | 1.057 | 2.015 | 0.022 |
∗
Risk factors with statistical significance in univariate Cox regression.
APACHE II indicates Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; COPD, chronic obstructive pulmonary disease; HR, hazard ratio.