TABLE 3.
Characteristics of 27 fecal Escherichia coli strains from 20 human and animal household members associated with present case 1 of hemorrhagic pneumonia due to E. coli
| Characteristic |
Prevalence of characteristic (no. [column %]) |
P value | Prevalence of characteristic (no. [column %]) |
P value | ||||
|---|---|---|---|---|---|---|---|---|
| Category | Specific variablea | Total (n = 27) | Non-B2 (n = 16) | B2 (n = 11) | cnf1 negative (n = 19) | cnf1 positive (n = 8) | ||
| Sequence type (ST) | STc12 or ST127 | 4 (15) | 0 (0) | 4 (36) | 0.02 | 0 (0) | 4 (50) | 0.004 |
| O type | O2, O4, or O6 | 7 (26) | 1 (6) | 6 (55) | 0.02 | 1 (5) | 6 (75) | <0.001 |
| Pathotype | ExPEC | 9 (33) | 0 (0) | 9 (82) | <0.001 | 1 (5) | 7 (88) | <0.001 |
| Adhesins | papAHCEFG, papG III | 8 (30) | 0 (0) | 8 (73) | <0.001 | 0 (0) | 8 (100) | <0.001 |
| sfa/focDE | 8 (30) | 0 (0) | 8 (73) | <0.001 | 1 (5) | 7 (88) | <0.001 | |
| hra | 10 (37) | 2 (13) | 8 (73) | 0.003 | 2 (11) | 8 (100) | <0.001 | |
| Toxins | hlyA | 8 (30) | 0 (0) | 8 (73) | <0.001 | 0 (0) | 8 (100) | <0.001 |
| cnf1 | 8 (30) | 0 (0) | 8 (73) | <0.001 | NAb | NA | NA | |
| vat | 10 (37) | 0 (0) | 10 (91) | <0.001 | 2 (11) | 8 (100) | <0.001 | |
| Iron acquisition | iroN | 9 (33) | 0 (0) | 9 (82) | <0.001 | 2 (11) | 7 (88) | <0.001 |
| fyuA | 12 (44) | 2 (13) | 10 (91) | <0.001 | 4 (21) | 8 (100) | <0.001 | |
| ireA | 4 (15) | 0 (0) | 4 (36) | 0.02 | 0 (0) | 4 (50) | 0.004 | |
| Protectins | kpsMII or kpsMTIII | 8 (30) | 0 (0) | 8 (73) | <0.001 | 1 (5) | 7 (88) | <0.001 |
| Miscellaneous | usp | 10 (37) | 0 (0) | 10 (91) | <0.001 | 2 (11) | 8 (100) | <0.001 |
| ibeA | 4 (15) | 0 (0) | 4 (36) | 0.02 | 2 (11) | 2 (25) | 0.56 | |
| ompT | 16 (59) | 6 (38) | 10 (91) | 0.008 | 9 (47) | 7 (88) | 0.09 | |
| malX | 10 (37) | 0 (0) | 10 (91) | <0.001 | 2 (11) | 8 (100) | <0.001 | |
| clbB/N | 6 (22) | 0 (0) | 6 (55) | 0.002 | 0 (0) | 6 (75) | <0.001 | |
Variables shown are those that yielded P < 0.05 for at least one comparison. Definitions: clb/N (colibactin synthesis), cnf1 (cytotoxic necrotizing factor), ExPEC (extraintestinal pathogenic E. coli), fyuA (yersiniabactin), hlyA (alpha hemolysin), hra (heat-resistant agglutinin), ibeA (invasion of brain endothelium A), ireA (siderophore receptor), iroN (salmochelin receptor), kpsMII (group 2 capsules), kpsMTIII (group 3 capsules), malX (pathogenicity island marker), ompT (outer membrane protein T), papAHCEFG (P fimbriae); papG allele III (P adhesin variant), sfa/focDE (S and F1C fimbriae), STc (ST complex); usp (uropathogenic-specific protein), vat (vacuolating toxin).
NA, not applicable (cnf1 status was invariant within each group).