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. Author manuscript; available in PMC: 2021 Nov 10.
Published in final edited form as: ACS Catal. 2019 Nov 7;9(12):11709–11719. doi: 10.1021/acscatal.9b03840

Table 2.

Specific Activities of the WT and Mut 6–1 on NAD(P)+ and mNAD+sa

graphic file with name nihms-1735304-t0001.jpg
specific activity (U/mg)
coenzyme WT Mut 6–1 fold change (Mut 6–1/wild-type)
NADP+ 18.0 ± 0.8 27.1 ± 0.8 1.5
NAD+ 4.9 ± 0.2 28.5 ± 0.2 5.8
NGD+ 6.9 ± 0.5 28.7 ± 2.8 4.1
NHD+ 6.4 ± 0.1 40.4 ± 0.1 6.3
NMN+ 0.60 ± 0.01 17.7 ± 0.35 29.5
NR+ (1.8 ± 0.1) × 10−3 (1.3 ± 0.1) × 10−2 7
BNA+ (3.5 ± 0.6) × 10−4 (3.1 ± 0.2) × 10−3 8.9
a

Each value represents the average ± standard deviation of triplicate independent measurements.