TABLE 1.

Temperature and drug sensitivities of wild-type and mutant strains

Strain or genotype	Growth
	YPD			Cycloheximide, 0.4 μg/μl	Hygromycin B, 25 μg/μl	Caffeine, 7.5 mM	Formamide, 3%	Rapamycin, 5 μg/μl	Oligomycin, 1.5 μg/μl
	16°C	30°C	37°C
KY898	++	++	++	++	++	++	++	++	++
Δaca1	++	++	++	++	++	++	++	++	++
Δaca2	−	+	+	−	±	++	−	+	±
Δaca1 Δaca2	−	+	+	−	±	++	−	+	±
Δacr1	++	++	++	++	++	−	+	++	++
Δacr1 Δaca1	++	++	++	++	++	+	+	++	++
Δacr1 Δaca2	−	+	+	−	±	+	−	+	±
Δacr1 Δaca1 Δaca2	−	+	+	−	++	++	−	+	±
2μm-Aca1 in Δaca2	++	++	NDa	ND	ND	ND	ND	ND	ND

^aND, not determined.