Skip to main content
. Author manuscript; available in PMC: 2022 Mar 8.
Published in final edited form as: Curr Biol. 2020 Dec 3;31(5):911–922.e4. doi: 10.1016/j.cub.2020.11.028

Figure 7. Electrical features of Xiphophorus hellerii Kcnh8.

Figure 7.

(A) Representative TEVC recordings of Kcnh8-expressing Xenopus oocytes at the indicated potassium concentrations. Test voltages ranged between +40 to −140 mV in 10 mV decrements. (B) Steady-state currents (ISS) extracted from recordings as shown in (A) of Kcnh8-expressing oocytes were plotted as a function of the applied membrane potential (mean of n ≥ 7 oocytes ± SD of ≥ 3 independent experiments). (C) Application of 10 mM BaCl2 in the presence of 30 mM KCl inhibited the KCNH8-mediated ISS (mean of n = 6 oocytes ± SD of ≥ 2 independent experiments). (B) and (C) ISS were normalized to the currents at +30 mV in standard bath medium (30 mM KCl). See also Figure S5.