Table 1.

Quantitative data for tau + shRNA axonal transport experiments

Experimental conditions	Anterograde segment velocity (µm/s)	Retrograde segment velocity (µm/s)	Total pause frequency (pauses/s)	Anterograde pause frequency (pauses/s)	Retrograde pause frequency (pauses/s)
Control shRNA
WT tau	1.81 ± 0.33	1.93 ± 0.22	0.155 ± 0.038	0.072 ± 0.028	0.121 ± 0.025
P301L tau	2.00 ± 0.37	2.24 ± 0.27	0.356 ± 0.109	0.184 ± 0.055	0.206 ± 0.085
R5L tau	2.10 ± 0.34	2.32 ± 0.34	0.336 ± 0.112	0.206 ± 0.057	0.226 ± 0.086
PP1α shRNA
WT tau	2.22 ± 0.36	2.26 ± 0.11	0.222 ± 0.039	0.158 ± 0.049	0.169 ± 0.025
P301L tau	2.30 ± 0.56	2.36 ± 0.27	0.339 ± 0.051	0.230 ± 0.063	0.237 ± 0.022
R5L tau	2.30 ± 0.20	2.24 ± 0.25	0.324 ± 0.059	0.253 ± 0.082	0.175 ± 0.040
PP1γ shRNA
WT tau	1.85 ± 0.43	2.01 ± 0.29	0.168 ± 0.032	0.089 ± 0.019	0.126 ± 0.035
P301L tau	1.96 ± 0.30	2.08 ± 0.30	0.156 ± 0.020	0.087 ± 0.010	0.106 ± 0.015
R5L tau	2.00 ± 0.15	2.06 ± 0.21	0.227 ± 0.035	0.139 ± 0.046	0.155 ± 0.043

This table includes mean values ± SD for axonal transport directional segment velocities and total and directional pause frequencies from the tau expression groups within each shRNA treatment group (Fig. 7E–I).