Table 2.

Two-way ANOVA Tukey's post hoc multiple comparison analysis for tau + shRNA axonal transport pause frequency data

Comparison	Total	Anterograde	Retrograde
Control shRNA
WT tau versus P301L tau	p < 0.0001	p = 0.0100	p = 0.0109
WT tau versus R5L tau	p < 0.0001	p < 0.0001	p = 0.0014
P301L tau versus R5L tau	p = 0.8466	p = 0.7316	p = 0.7547
PP1α shRNA
WT tau versus P301L tau	p = 0.0073	p = 0.0450	p = 0.0536
WT tau versus R5L tau	p = 0.0209	p = 0.0058	p = 0.9797
P301L tau versus R5L tau	p = 0.9163	p = 0.7061	p = 0.0821
PP1γ shRNA
WT tau versus P301L tau	p = 0.9457	p = 0.9974	p = 0.7415
WT tau versus R5L tau	p = 0.2491	p = 0.2119	p = 0.5665
P301L tau versus R5L tau	p = 0.1406	p = 0.1875	p = 0.1939

This table includes the adjusted p values for the comparisons between tau expression groups within each shRNA treatment group for axonal transport total and directional pause frequencies. Data (Fig. 7G–I) was analyzed by two-way ANOVA with Tukey's multiple comparison test. Significance was established at an adjusted p ≤ 0.05.