Table 2:

Grade 2 and 3 adverse events by CTCAE 4.0

Adverse Events (CTCAE 4.0)	Grade 2, N (%)	Grade 3, N (%)
Blood and lymphatic system disorders:
Anemia	3 (12%)	1 (4%)
Lymphocyte count decreased	5 (20%)	1 (4%)
Neutrophil count decreased	0 (0%)	1 (4%)
Platelet count decreased	1 (4%)	0 (4%)
White blood cell count decreased	3 (12%)	1 (4%)
Gastrointestinal disorders:
Abdominal pain	2 (8%)	2 (8%)
Diarrhea	11 (44%)	5 (20%)
Nausea	3 (12%)	1 (4%)
Vomiting	0 (0%)	2 (8%)
General:
Anorexia	2 (8%)	1 (4%)
Dehydration	2 (8%)	1 (4%)
Fatigue	2 (8%)	1 (4%)
Generalized muscle weakness	1 (4%)	0 (0%)
Weight loss	1 (4%)	1 (4%)
Laboratory abnormalities:
Acute kidney injury	0 (0%)	1 (4%)
Aspartate aminotransferase increased	1 (4%)	0 (0%)
Creatinine increased	1 (4%)	0 (0%)
Hypoalbuminemia	1 (4%)	0 (0%)
Skin:
Rash maculo-papular	1 (4%)	0 (0%)
Skin laceration	1 (4%)	0 (0%)
Cardiovascular disorders:
Ejection fraction decreased	1 (4%)	0 (0%)
Hypertension	0 (0%)	1 (4%)
Syncope	0 (0%)	1 (4%)