Fig 7. Mean change in concentration from pre-infusion to Day 10 post-infusion of patients with and without CPT.

The mean change (Δ) in cytokine concentration between pre-infusion levels (Day 0) and Day 10 post-infusion for CPT patients and corresponding10-day period for nonCPT treated patients were calculated in patients categorized as Track 2 (A) and Track 3 (B). Statistically significant changes in mean values between those patient who received CPT (Track 2, n = 22; Track 3, n = 10) and those who did not (nonCPT; Track 2, n = 8; Track 3, n = 10) were evaluated via T-test. Significance is denoted by (*) for 0.01≤p≤0.05 or (**) for p<0.01.