Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 10;7(46):eabi8178. doi: 10.1126/sciadv.abi8178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

PMC Copyright notice

Fig. 4. — Results of GSEA analyses for the 17 gene sets identified as dysregulated in both YAPS and at least one AD cohort. Comparing overlapping gene sets between YAPS and AD cohorts (ROS/BLSA), gene sets had significant and opposite expression in YAPS relative to the AD cohorts. The gene set name is given on the y axis, and NES is provided on the x axis. A positive NES indicates a significant positive enrichment of the gene set such that this pathway may be overexpressed in the cohort. A negative NES indicates a negative enrichment of the gene set such that this pathway may be underexpressed in the cohort. Bars are colored according to cohort.